Transient "sicca syndrome" during phenobarbital treatment.
J Neurol Sci
; 300(1-2): 164, 2011 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-20951387
ABSTRACT
Even after the introduction of new antiepileptic drugs, phenobarbital continues to be largely used in the treatment of epilepsy. We report the case of a 59-year-old woman with focal seizures with secondary generalization, treated with phenobarbital with normal serum levels. After thirty days she showed Sjogren-like symptoms, which resolved after the replaced of phenobarbital with oxcarbazepine. Although many antiepileptic drugs are known to induce autoimmune disorders, a "Sicca Syndrome" has never been reported as an adverse effect of phenobarbital. We think this case report leads to take into consideration the possibility of a drug-induced disorder whenever patients treated with barbiturates develop symptoms suggestive of Sjogren's Syndrome.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fenobarbital
/
Síndrome de Sjögren
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Anticonvulsivantes
Límite:
Female
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Humans
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Middle aged
Idioma:
En
Revista:
J Neurol Sci
Año:
2011
Tipo del documento:
Article
País de afiliación:
Italia