[Mechanism of action and applications for glucose analogs]. / Mechanizm dzialania i zastosowanie analogów glukozy.

ABSTRACT

The paper presents recent problems of the mechanism of the action of glucose analogs (especially 2-deoxy-D-glucose and 5-thio-D-glucose) at the cellular level as well as their application in experimental and clinical medicine. It has been discussed, whether 2-DG and 5-TG could be assumed to represent nonmetabolizable antimetabolites of glucose.