Are glucocorticoids auto- and/or paracrine factors in early bovine embryo development and implantation?
Reprod Biol
; 10(3): 249-56, 2010 Nov.
Article
en En
| MEDLINE
| ID: mdl-21113206
ABSTRACT
We determined the transcript content of three genes involved in the metabolism of glucocorticoids (GC) in bovine in vitro fertilized embryos (2-blastomere stage until hatched blastocyst), trophoblast as well as the oviduct (Day 2-4 of the estrous cycle) and endometrium (Day 16 of the cycle and pregnancy). Since mRNA expression of the glucocorticoid receptor and two enzymes responsible for GC production (11ß-HSD1 and 2) was demonstrated in the embryos in all pre-implantation stages as well as in the endometrium and oviduct, it is suggested that GC may serve as auto-/paracrine factors in the development of bovine pre-implantation embryos.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Implantación del Embrión
/
Bovinos
/
Receptores de Glucocorticoides
/
Comunicación Autocrina
/
Comunicación Paracrina
/
Glucocorticoides
Límite:
Animals
Idioma:
En
Revista:
Reprod Biol
Asunto de la revista:
MEDICINA REPRODUTIVA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Polonia