[Dynamics of the incidence of Creutzfeldt-Jakob disease in Slovakia in 1975-2008]. / Dynamika výskytu Creutzfeldtovej-Jakobovej choroby na Slovensku v rokoch 1975-2008.

ABSTRACT

The paper reports on Creutzfeldt-Jakob disease (CJD) occurrence in Slovakia in years 1975-2008. Changes in the incidence of this most important human prion disease, occurrence of individual forms of the classical CJD variant and the unique, unusually high proportion of genetic CJD are documented. Endo- and exogenous risk factors are analyzed, gaps in the prevention of iatrogenic infection are pointed out and the prophylaxis of genetic CJD is discussed.