Effect of bioregulators isolated from the liver, blood serum, and bile of mammals on the state of newt liver tissue in organotypic culture.
Bull Exp Biol Med
; 150(1): 140-8, 2010 Dec.
Article
en En
| MEDLINE
| ID: mdl-21161073
ABSTRACT
We developed models of in vitro organotypic culturing of newt liver tissue with and without adhesion to the substrate. The effects of bioregulators isolated from mammalian liver, blood serum, and bile were studied on the developed models and their specificity was demonstrated. The state of the liver was evaluated by the area of clusters of pigmented cells and by the number of mitoses in the connective tissue cells of the cortical layer. These bioregulators exhibited their biological effects only under conditions of roller organotypic culturing of newt liver tissue.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Técnicas de Cultivo de Órganos
/
Bilis
/
Sustancias de Crecimiento
/
Hígado
Límite:
Animals
Idioma:
En
Revista:
Bull Exp Biol Med
Año:
2010
Tipo del documento:
Article
País de afiliación:
Rusia