[Receptor system of brain vessels in arterial hypertension].

ABSTRACT

We conducted a post-mortem study of the receptor system of brain vessels in patients with arterial hypertension (AG), stages I-III, and healthy people using impregnation and a method of measuring NADPH-diaphorase. The receptor system of arterial wall is represented by treelike and glomerular structures with moderate enzyme activity. Reactive and destructive disturbances of the receptor system that were distinctly seen on histochemical preparations were found in brain arteries of AG patients. The intensity of changes in the nervous apparatus of brain vessels was closely related to the artery caliber, their localization, disease duration and severity, with the most early and deep changes in the afferent fibers and receptors of the pia mater arteries. In intracerebral arteries, reactive changes in receptor structures were found in long-term hypertension and destructive changes were found in AG, stages II-III.