Induction of tributyltin-binding protein type 2 in Japanese flounder, Paralichthys olivaceus, by exposure to tributyltin-d27.
Mar Pollut Bull
; 62(2): 412-4, 2011 Feb.
Article
en En
| MEDLINE
| ID: mdl-21232774
ABSTRACT
In this study, individual Japanese flounder were intraperitoneally injected with 2 µg tributyltin-d27 (TBT-d27) fish⻹. Blood samples were collected on day 7 after injection. TBT-binding protein types 1 and 2 (TBT-bp1, -bp2) in the blood serum were quantified by western blotting analysis. As a result, the concentration of TBT-bp2 in TBT-d27 treated group increased to 220% of that in the solvent control, whereas the TBT-bp1 concentration decreased to 65% of that in the solvent control. Additionally, a positive relationship between the concentrations of TBT-bp2 and TBT was observed in blood sera of wild and cultured flounder. We suggest that TBT-bp2 is produced in response to TBT exposure and may play an important role in fish physiology.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos de Trialquiltina
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Lenguado
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Proteínas Portadoras
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Proteínas de Peces
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Disruptores Endocrinos
Límite:
Animals
Idioma:
En
Revista:
Mar Pollut Bull
Año:
2011
Tipo del documento:
Article
País de afiliación:
Japón