Phenylpropanoids from the leaves of Acanthopanax koreanum and their antioxidant activity.
J Asian Nat Prod Res
; 13(1): 56-61, 2011 Jan.
Article
en En
| MEDLINE
| ID: mdl-21253950
ABSTRACT
By various chromatographic methods, one new phenylpropanoid, acanthopanic acid (1), and three known compounds, 1,2-O-dicaffeoylcyclopenta-3-ol (2), (4S)-α-terpineol 8-O-ß-D-glucopyranoside (3), and rutin (4), were isolated from the methanol extract of the Acanthopanax koreanum leaves. Their structures were elucidated on the basis of spectroscopic analyses, and their antioxidant activities were evaluated by the intracellular reactive oxygen species (ROS) radical scavenging 2',7'-dichlorofluorescein diacetate assay. Among them, compounds 1, 2, and 4 showed significant scavenging capacity with IC(50) values of 3.8, 2.6, and 2.9 µM, respectively, and compound 3 showed weak scavenging capacity with the inhibition rate of 37% at 40 µM.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fenilpropionatos
/
Eleutherococcus
/
Glicósidos
/
Antioxidantes
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Asian Nat Prod Res
Asunto de la revista:
BOTANICA
/
QUIMICA
Año:
2011
Tipo del documento:
Article