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Recent findings in the epidemiology, diagnosis and treatment of superficial-vein thrombosis.
Décousus, Hervé; Bertoletti, Laurent; Frappé, Paul; Becker, François; Jaouhari, Asma El; Mismetti, Patrick; Moulin, Nathalie; Presles, Emilie; Quéré, Isabelle; Leizorovicz, Alain.
Afiliación
  • Décousus H; INSERM, CIE3, Université Jean Monnet, EA3065, CHU Saint-Etienne, Service de Médecine et Thérapeutique, Saint-Etienne, F-42055 France. herve.decousus@chu-st-etienne.fr
Thromb Res ; 127 Suppl 3: S81-5, 2011 Feb.
Article en En | MEDLINE | ID: mdl-21262449
Recent data on lower-limb superficial-vein thrombosis (SVT) may substantially impact its clinical management. Thus, the clear confirmation that SVT is closely linked to deep-vein thrombosis (DVT) or pulmonary embolism (PE) highlights the potential severity of the disease. DVT or PE are diagnosed in 20-30% of SVT patients. Moreover, clinically relevant symptomatic thromboembolic events complicate isolated SVT (without concomitant DVT or PE at diagnosis) in 4-8% of patients. For the first time, an anticoagulant treatment, once-daily 2.5 mg fondaparinux for 45 days, was demonstrated to be effective and safe for preventing these symptomatic thromboembolic events in patients with lower-limb isolated SVT in the randomized placebo-controlled CALISTO study. Based on these recent findings, new recommendations on the management of SVT patients, including complete ultrasonography examination of the legs, and in patients with isolated SVT, prescription of once-daily 2.5 mg fondaparinux subcutaneously for 45 days on top of symptomatic treatments, may be proposed.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polisacáridos / Trombosis de la Vena / Extremidad Inferior / Anticoagulantes Tipo de estudio: Clinical_trials / Diagnostic_studies / Guideline / Screening_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Thromb Res Año: 2011 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polisacáridos / Trombosis de la Vena / Extremidad Inferior / Anticoagulantes Tipo de estudio: Clinical_trials / Diagnostic_studies / Guideline / Screening_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Thromb Res Año: 2011 Tipo del documento: Article Pais de publicación: Estados Unidos