Combined protective effects of anti-PhtD and anti-pneumococcal polysaccharides.
Vaccine
; 29(38): 6451-3, 2011 Sep 02.
Article
en En
| MEDLINE
| ID: mdl-21315695
ABSTRACT
In the past years, a significant rise in the proportion of childhood complicated pneumonia cases related to pneumococcal serotypes 1 and 3 has been observed. PhtD is a vaccine candidate protein antigen. By using a pneumococcal lethal intranasal challenge mouse model, a significant additive effect on protection was observed with the combination of vaccination-induced anti-PhtD and injected anti-polysaccharide antibodies specific for serotypes 1 and 3.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones Neumocócicas
/
Streptococcus pneumoniae
/
Vacunas Neumococicas
/
Anticuerpos Antibacterianos
Límite:
Animals
/
Female
/
Humans
Idioma:
En
Revista:
Vaccine
Año:
2011
Tipo del documento:
Article
País de afiliación:
Bélgica