CD4+CD28 null T lymphocytes are expanded in young women with polycystic ovary syndrome.
Fertil Steril
; 95(8): 2651-4, 2011 Jun 30.
Article
en En
| MEDLINE
| ID: mdl-21324454
ABSTRACT
Women affected by polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease. We demonstrated that women with PCOS showed an expansion of CD4(+)CD28(null) T cells, an aggressive population of T lymphocytes that has been recently associated with recurrent coronary instability and type 2 diabetes mellitus. This sheds new light on possible mechanisms responsible for the higher rate of cardiovascular disease among women with PCOS.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome del Ovario Poliquístico
/
Enfermedades Cardiovasculares
/
Linfocitos T CD4-Positivos
/
Antígenos CD28
/
Proliferación Celular
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Fertil Steril
Año:
2011
Tipo del documento:
Article
País de afiliación:
Italia