Systematic review of endoscopic airway findings in children with gastroesophageal reflux disease.
Ann Otol Rhinol Laryngol
; 120(2): 116-22, 2011 Feb.
Article
en En
| MEDLINE
| ID: mdl-21391424
ABSTRACT
OBJECTIVES:
We performed a systematic review of published literature correlating findings on endoscopic evaluation of the larynx and trachea in the pediatric population with the incidence of gastroesophageal reflux disease.METHODS:
Eight articles were identified through a structured PubMed search of English-language literature using the key terms laryngopharyngeal reflux, extraesophageal reflux, and gastroesophageal reflux. A systematic review was performed relating the presence of reflux in the pediatric population to findings on endoscopic airway evaluation. A covariant analysis was performed, and each study was weighted according to the number of available samples in that study as a fraction of the total. Overall odds ratios and confidence intervals were computed for each endoscopic finding on the basis of the documented absence or presence of gastroesophageal reflux disease.RESULTS:
A correlation was seen between the endoscopic findings and the presence of reflux.CONCLUSIONS:
Arytenoid, postglottic, and vocal fold edema and erythema, lingual tonsil hypertrophy, laryngomalacia, and subglottic stenosis are among the endoscopic findings most frequently identified in patients with gastroesophageal reflux disease. Certain findings commonly encountered on endoscopic evaluation of the larynx and trachea in children who present with respiratory symptoms do indeed demonstrate a correlation with the presence of laryngopharyngeal reflux disease and may indicate the need for antireflux therapy.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tráquea
/
Reflujo Gastroesofágico
/
Laringe
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Systematic_reviews
Idioma:
En
Revista:
Ann Otol Rhinol Laryngol
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA