[Effect of short-term intensive therapy with glimepiride and metformin in newly diagnosed type 2 diabetic patients].
Nan Fang Yi Ke Da Xue Xue Bao
; 31(3): 564-6, 2011 Mar.
Article
en Zh
| MEDLINE
| ID: mdl-21421509
ABSTRACT
OBJECTIVE:
To evaluate the effect of short-term intensive therapy on blood glucose control, BETA-cell function, and blood lipid levels in newly diagnosed type 2 diabetic patients.METHODS:
Out-patients with newly diagnosed type 2 diabetic patients were enrolled for intensive treatment with sulfonylureas and metformin for 12 weeks, and the therapeutic effect was evaluated.RESULTS:
After the intensive treatment, FPG, 2 hPG, and HbA1c decreased significantly (P<0.01); HOMA-IR decreased and HOMA-B increased significantly (P<0.01), and TG, CHOL, LDL decreased significantly (P<0.01) after the treatment.CONCLUSION:
Short-term intensive treatment with glimepiride combined with metformin is safe and effective in newly diagnosed type 2 diabetic patients with HbA1c>9%.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos de Sulfonilurea
/
Diabetes Mellitus Tipo 2
/
Metformina
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
/
Male
Idioma:
Zh
Revista:
Nan Fang Yi Ke Da Xue Xue Bao
Año:
2011
Tipo del documento:
Article
País de afiliación:
China