Matrix metalloproteinase 9 levels in gingival crevicular fluid in patients after periodontal microsurgery for orthodontic induced gingival hypertrophy.
Rom J Morphol Embryol
; 52(1 Suppl): 431-3, 2011.
Article
en En
| MEDLINE
| ID: mdl-21424088
ABSTRACT
INTRODUCTION:
In this study, we aim to compare the levels of matrix metalloproteinase 9 (MMP9) in the gingival crevicular fluid (GCF), as indicators for healing, in two groups of patients - operated with a classic periodontal surgical technique and the same technique but using a dental microscope. MATERIALS We included 14 patients with ages between 12 and 26 years, average 14±6.2 years. Eight patients were women and six men. All patients presented gingival hypertrophy because of the orthodontic treatment on the mandibular arch. We performed gingivectomy on one-half of the mandibular arch by classic periodontal surgery and on the other half of the mandibular arch by a microscope-assisted gingivectomy.METHODS:
In the hypertrophied gingiva, the expression of MMP9 was identified using immunohistochemical-staining techniques. For immunological determination of MMP9 in GCF we performed Elisa tests.RESULTS:
We found different levels in different moments of the healing process for the two hemiarcades.CONCLUSIONS:
We consider that faster healing in case of microscope-assisted gingivectomy may be related to the expression of MMP-9 in the GCF.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aparatos Ortodóncicos
/
Periodoncio
/
Líquido del Surco Gingival
/
Metaloproteinasa 9 de la Matriz
/
Hipertrofia Gingival
/
Microcirugia
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Rom J Morphol Embryol
Asunto de la revista:
ANATOMIA
/
EMBRIOLOGIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Rumanía