Highly regio- and diastereoselective anionic [3 + 2] cycloaddition under phase transfer catalytic conditions.

ABSTRACT

A highly trans and regioselective anionic formal [3 + 2] cycloaddition was achieved with allylic sulfones having an MBH acrylamide backbone under phase transfer organocatalytic conditions giving rise to the formation of unprecedented densely substituted cyclopentene derivatives.