Differential effects of cold exposure on gene expression profiles in white versus brown adipose tissue.
Appl Biochem Biotechnol
; 165(2): 538-47, 2011 Sep.
Article
en En
| MEDLINE
| ID: mdl-21556901
ABSTRACT
The thermogenic function of brown adipose tissue (BAT) is known to be markedly elevated when animals are exposed to the cold, and intensive studies have been carried out to understand the molecular basis enabling effective thermogenesis in cold-exposed animals. In this study, we used microarray analysis to examine the effects of cold exposure of animals on their gene expression profiles in white adipose tissue (WAT), which seems to function as a counterpart tissue of BAT. The results indicate that the effects of cold exposure on the gene expression profiles of WAT were much more moderate than the effects on those of BAT. Possible reasons for the different responses of BAT and WAT to cold exposure are discussed.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tejido Adiposo Pardo
/
Regulación de la Expresión Génica
/
Frío
/
Termogénesis
/
Metabolismo Energético
/
Tejido Adiposo Blanco
Límite:
Animals
Idioma:
En
Revista:
Appl Biochem Biotechnol
Año:
2011
Tipo del documento:
Article
País de afiliación:
Japón