Association of the intronic rs2072621 polymorphism of the X-linked GPR50 gene with affective disorder with seasonal pattern.
Eur Psychiatry
; 27(5): 369-71, 2012 Jul.
Article
en En
| MEDLINE
| ID: mdl-21565467
ABSTRACT
This case-control study found an association between Seasonal Affective Disorder (SAD) and a single nucleotide polymorphism (intronic rs2072621) of the gene encoding GPR50 (an orphan member of the G protein-coupled melatonin receptor subfamily) in females. This may represent a gender-specific risk factor and a molecular link between melatonin and SAD.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Intrones
/
Trastorno Afectivo Estacional
/
Polimorfismo de Nucleótido Simple
/
Receptores Acoplados a Proteínas G
/
Genes Ligados a X
/
Proteínas del Tejido Nervioso
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur Psychiatry
Asunto de la revista:
PSIQUIATRIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Francia