[Periprosthetic infections following total hip replacement with ESBL-forming bacteria: importance for clinical practice]. / Periprothetische Infektionen nach Hüfttotalendoprothese mit ESBL-bildenden Bakterien: Bedeutung für die klinische Praxis.
Orthopade
; 40(6): 528-34, 2011 Jun.
Article
en De
| MEDLINE
| ID: mdl-21584734
Implant infections remain feared and severe complications after total hip replacement. An even higher rate of periprosthetic infections can be observed after revision surgery in comparison to primary total hip replacement. An additional threat for patients with artificial joints arises from the fact that bacteria resistant to a multitude of antibiotics are encountered with increasing frequency in the hospital setting.Among these the enterobacteria producing extended spectrum ß-lactamases (ESBL) are the second most frequent group of multiresistant pathogens. ESBLs are enzymes which possess the ability to hydrolyse third and fourth generation cephalosporins resulting in a distinctive resistance against these antibiotics. Even though ESBLs were first described in the early 1980's and now represent pathogens of utmost importance in intensive care units, they have been hardly considered in orthopedic and trauma surgery.In the present manuscript we provide an overview of the epidemiology and diagnostics of ESBL-expressing bacteria and demonstrate the difficulties in managing implant-associated infections with resistant bacteria. Furthermore, we emphasize the importance of recognizing ESBL-positive bacteria as increasingly important pathogens which require special precautions and treatment. Clinical evaluations suggest that ESBLs in orthopedic and trauma surgery are not a rare phenomenon any more.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Artroplastia de Reemplazo de Cadera
/
Infecciones por Enterobacteriaceae
/
Prótesis de Cadera
Límite:
Humans
Idioma:
De
Revista:
Orthopade
Año:
2011
Tipo del documento:
Article
Pais de publicación:
Alemania