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Biomechanical study on the edge shapes for penetrating keratoplasty.
Lee, Heow Pueh; Zhuang, Han.
Afiliación
  • Lee HP; Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, 117576 Singapore. mpeleehp@nus.edu.sg
Article en En | MEDLINE | ID: mdl-21604219
A parametric study to investigate the compressive and the shear stress distributions for various edge shapes created during penetrating keratoplasty (PK) using femtosecond laser is reported. The finite element analysis has been implemented using ABAQUS to study the cornea with various edge shapes, namely the standard edge shape, the zigzag edge shape, the top hat edge shape and the mushroom edge shape for PK. The ratio of maximum compressive stress to maximum shear stress is used as the main factor to assess the relative merits of wound healing rate for different edge shapes. For the typical values of tissue mechanical properties, the zigzag edge shape has the highest ratio of maximum compressive stress to maximum shear stress (11.1 in the xy-direction and 3.7 in the yz-direction), followed by the mushroom edge shape (7.7 in the xy-direction and 3.2 in the yz-direction). The ratios for the top hat and the standard edge shapes are even lower in both directions. A sensitivity analysis of the model has been done to demonstrate that the zigzag edge shape always results in the highest ratios of stresses regardless of the difference in the tissue mechanical properties. The zigzag edge shape also gives the lowest dioptric power D = 45.4. The present results imply that the zigzag edge shape provides the best wound healing rate and optical outcome among the four edge shapes models for PK.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Queratoplastia Penetrante / Córnea / Cirugía Asistida por Computador / Modelos Biológicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Comput Methods Biomech Biomed Engin Asunto de la revista: ENGENHARIA BIOMEDICA / FISIOLOGIA Año: 2012 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Queratoplastia Penetrante / Córnea / Cirugía Asistida por Computador / Modelos Biológicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Comput Methods Biomech Biomed Engin Asunto de la revista: ENGENHARIA BIOMEDICA / FISIOLOGIA Año: 2012 Tipo del documento: Article Pais de publicación: Reino Unido