Free radical scavenging and hepatoprotective potential of Ficus microcarpa L. fil. bark extracts.
J Nat Med
; 65(3-4): 633-40, 2011 Jul.
Article
en En
| MEDLINE
| ID: mdl-21625948
ABSTRACT
Successive extracts of Ficus microcarpa L. fil. bark (FMB) were tested for antioxidant and hepatoprotective activity against carbon tetrachloride- and paracetamol-induced hepatotoxicities in rats. The ethyl acetate extract of FMB exhibited significant antioxidant and hepatoprotective activity by reducing carbon tetrachloride- and paracetamol-induced changes in biochemical parameters as evidenced by enzymatic and histological examination. Pretreatment with ethyl acetate extract of FMB significantly shortened the duration of pentobarbitone-induced necrosis in mice, indicating its hepatoprotective potential. Phytochemical studies confirmed the presence of the phenolic compound, catechin, in FMB, which may interfere with free-radical formation and may account for its significant hepatoprotective effects. The present study thus provides a scientific rationale for the traditional use of this plant in the management of liver disorders.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
/
Depuradores de Radicales Libres
/
Ficus
/
Corteza de la Planta
Límite:
Animals
Idioma:
En
Revista:
J Nat Med
Asunto de la revista:
TERAPIAS COMPLEMENTARES
Año:
2011
Tipo del documento:
Article
País de afiliación:
India