Locoregional therapy for hepatocellular carcinoma: radioembolization with yttrium-90 microspheres.
Minerva Gastroenterol Dietol
; 57(3): 287-98, 2011 Sep.
Article
en En
| MEDLINE
| ID: mdl-21769078
ABSTRACT
Compared with other malignant tumours, hepatocellular carcinoma (HCC) exhibits particular characteristics regarding its supplying vessels and tumour biology. If a potentially curative surgical approach, such as resection or liver transplantation, is due to technical or prognostical reasons no option, these characteristics are a fundamental prerequisite for the possibility to effectively treat this tumour by local ablation methods. Microsphere and particle technology with selective transport of tumoricidal substances or radiation represents a new generation of therapeutics in interventional oncology. With the intrahepatic application of radioactive microspheres via the hepatic artery (radioembolization) local ablation can be performed even of diffuse and multifocal liver tumours, which hitherto, could only be approached with systemic therapy. The present standard for radioembolization, is the use of yttrium-90 glass or resin microspheres. The indications, technique and current results of radioembolization with yttrium-90 microspheres for the treatment of HCC are discussed in this review.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Radioisótopos de Itrio
/
Carcinoma Hepatocelular
/
Embolización Terapéutica
/
Neoplasias Hepáticas
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Minerva Gastroenterol Dietol
Asunto de la revista:
CIENCIAS DA NUTRICAO
/
GASTROENTEROLOGIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Alemania