Precocious puberty in an infant with hepatoblastoma: a case report.
J Med Case Rep
; 5: 422, 2011 Aug 30.
Article
en En
| MEDLINE
| ID: mdl-21878089
ABSTRACT
INTRODUCTION:
The syndrome of isosexual precocious puberty associated with primary malignant hepatic tumors is rare. All previously reported cases in the literature are old and prognosis was grim. CASE PRESENTATION We present the case of a 15-month-old Asian male baby who presented with precocious puberty associated with hepatoblastoma. Serum concentrations of alpha-fetoprotein and free testosterone were elevated, as was beta human chorionic gonadotropin hormone. He was treated with six courses of chemotherapy and underwent surgery. His surface markers as well as free testosterone level returned to normal during therapy. The child has now been off therapy for 18 months with no evidence of tumor recurrence at follow-up.CONCLUSION:
Virilizing hepatoblastoma is rare and reported with poor outcome, but the development of new chemotherapeutic agents and complete surgical resection are promising.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
J Med Case Rep
Año:
2011
Tipo del documento:
Article
País de afiliación:
Jordania