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Relative safety of 4 weeks of blood flow-restricted resistance exercise in young, healthy adults.
Clark, B C; Manini, T M; Hoffman, R L; Williams, P S; Guiler, M K; Knutson, M J; McGlynn, M L; Kushnick, M R.
Afiliación
  • Clark BC; Department of Biomedical Sciences, Institute for Neuromusculoskeletal Research, Ohio University, Athens, Ohio 45701, USA. clarkb2@ohio.edu
Scand J Med Sci Sports ; 21(5): 653-62, 2011 Oct.
Article en En | MEDLINE | ID: mdl-21917016
ABSTRACT
This study evaluated the effect of 4 weeks of low-load resistance exercise with blood flow restriction (BFRE) on increasing strength in comparison with high-load resistance exercise (HLE), and assessed changes in blood, vascular and neural function. Healthy adults performed leg extension BFRE or HLE 3 days/week at 30% and 80% of strength, respectively. During BFRE, a cuff on the upper leg was inflated to 30% above systolic blood pressure. Strength, pulse-wave velocity (PWV), ankle-brachial index (ABI), prothrombin time (PT) and nerve conduction (NC) were measured before and after training. Markers of coagulation (fibrinogen and D-dimer), fibrinolysis [tissue plasminogen activator (tPA)] and inflammation [high sensitivity C-reactive protein (hsCRP)] were measured in response to the first and last exercise bouts. Strength increased 8% with BFRE and 13% with HLE (P<0.01). No changes in PWV, ABI, PT or NC were observed following training for either group (P>0.05). tPA antigen increased 30-40% immediately following acute bouts of BFRE and HLE (P=0.01). No changes were observed in fibrinogen, D-dimer or hsCRP (P>0.05). These findings indicate that both protocols increase the strength without altering nerve or vascular function, and that a single bout of both protocols increases fibrinolytic activity without altering selected markers of coagulation or inflammation in healthy individuals.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adaptación Fisiológica / Ejercicio Físico / Músculo Esquelético / Pierna Límite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Scand J Med Sci Sports Asunto de la revista: MEDICINA ESPORTIVA Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adaptación Fisiológica / Ejercicio Físico / Músculo Esquelético / Pierna Límite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Scand J Med Sci Sports Asunto de la revista: MEDICINA ESPORTIVA Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos
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