Regulation of Drosophila-virus interaction.
Dev Comp Immunol
; 36(2): 262-6, 2012 Feb.
Article
en En
| MEDLINE
| ID: mdl-21925207
ABSTRACT
Drosophila melanogaster is a useful model system for deciphering mammalian biological processes including development, innate immunity and cancer. Most genetic studies conducted in Drosophila have focused on the immune response against microbial infection and the results obtained have been extrapolated to other organisms. During the last decade the issue of the antiviral response attracted a great deal of interest. In this review we highlight recent discoveries in the role of RNA interference pathway in antiviral response in Drosophila with a focus on the role of miRNAs as both host defense elements and helpers of viral replication.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Virus ARN
/
Drosophila melanogaster
/
Virus de Insectos
Límite:
Animals
Idioma:
En
Revista:
Dev Comp Immunol
Año:
2012
Tipo del documento:
Article
País de afiliación:
España