Thrombotic microangiopathy induced by long-term interferon-ß therapy for multiple sclerosis: a case report.
Clin Nephrol
; 76(5): 396-400, 2011 Nov.
Article
en En
| MEDLINE
| ID: mdl-22000560
We report the case of a 53-year-old woman treated for 8 years with Betaferon® (interferon-ß-1b), who developed mild renal failure with hypertension, proteinuria and glomerular hematuria. Kidney biopsy was consistent with thrombotic microangiopathy (TMA). Considering the strong evidence of interferon-α causing TMA and the numerous immunomodulatory activities shared by INF-α and -ß, we incriminated Betaferon as the etiological agent of TMA in our patient. To our knowledge, it is the first time such an association has been published.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Adyuvantes Inmunológicos
/
Interferón beta
/
Microangiopatías Trombóticas
/
Lesión Renal Aguda
/
Esclerosis Múltiple
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Clin Nephrol
Año:
2011
Tipo del documento:
Article
País de afiliación:
Bélgica
Pais de publicación:
Alemania