Premorbid personality traits and their course in mild cognitive impairment: results from a prospective population-based study in Germany.
Dement Geriatr Cogn Disord
; 32(3): 171-7, 2011.
Article
en En
| MEDLINE
| ID: mdl-22005607
ABSTRACT
BACKGROUND:
Personality traits contribute to cognitive functioning. We present a study comparing personality traits in normal ageing and mild cognitive impairment (MCI).METHODS:
We conducted a representative longitudinal study including 222 subjects from a cohort born between 1930 and 1932 (n = 500) examined at three examination waves (t1 1993/1994; t2 1997/1998; t3 2005/2007). Personality traits were assessed with the NEO-Five-Factor Inventory questionnaire.RESULTS:
Healthy controls and patients with MCI showed a significant (p < 0.05) decrease concerning their levels of neuroticism and extraversion over time. MCI subjects scored significantly higher on neuroticism at baseline and lower on openness at all examinations compared to healthy controls. Subjects with higher baseline neuroticism showed a 2.24 times higher risk of developing MCI at the third follow-up (odds ratio = 2.24, 95% confidence interval = 1.12-4.45 - scores adjusted for education and sex).CONCLUSIONS:
MCI subjects differ in their premorbid personality traits compared to healthy controls. According to our study, higher neuroticism should be considered a risk factor for the development of MCI.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Personalidad
/
Disfunción Cognitiva
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Dement Geriatr Cogn Disord
Asunto de la revista:
GERIATRIA
/
NEUROLOGIA
/
PSIQUIATRIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Alemania