[Does paracetamol improve recovery after stroke?]. / Verbetert paracetamol het herstel na een beroerte?
Ned Tijdschr Geneeskd
; 155(46): A4169, 2011.
Article
en Nl
| MEDLINE
| ID: mdl-22108464
ABSTRACT
An increase in body temperature in the first days following stroke is related to poor functional outcome. High-dose paracetamol (acetaminophen) reduces the body temperature by 0.3°C and can prevent fever. Paracetamol treatment is simple, cheap and has few side effects. In the first "Paracetamol (Acetaminophen) in Stroke" (PAIS) study, there was a beneficial effect of high-dose paracetamol on functional outcome in patients with stroke and a body temperature of 37.0°C or above. Because this result was found in a subgroup analysis, a new study is needed to confirm this finding. Recently the randomised PAIS 2 study was initiated. This study aims to assess the effect of high-dose paracetamol on functional outcome in patients with acute stoke and a body temperature of 37.0°C or above.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antiinflamatorios no Esteroideos
/
Hipotermia Inducida
/
Acetaminofén
Tipo de estudio:
Clinical_trials
Límite:
Humans
Idioma:
Nl
Revista:
Ned Tijdschr Geneeskd
Año:
2011
Tipo del documento:
Article
País de afiliación:
Países Bajos