[Antibiotic dose adjustment in the treatment of MRSA infections in patients with acute renal failure undergoing continuous renal replacement therapies]. / Dosificación de antibióticos en el tratamiento de las infecciones por SARM en pacientes con insuficiencia renal aguda sometidos a técnicas continuas de depuración extrarrenal.
Enferm Infecc Microbiol Clin
; 30(5): 249-56, 2012 May.
Article
en Es
| MEDLINE
| ID: mdl-22130573
ABSTRACT
Acute renal failure is frequent in critically ill patients. In those patients who need renal replacement therapy, continuous techniques are an alternative to intermittent haemodialysis. Critically ill patients often have an infection, which can lead to sepsis and renal failure. An early and adequate antibiotic treatment at correct dosage is extremely important. Methicillin resistant Staphylococcus aureus (MRSA) is a frequent nosocomial pathogen that causes a high rate of morbidity and mortality in critically ill patients. Many antibiotics are easily removed by continuous renal replacement therapies (CRRT) leading to a high risk of under dosing and therapeutic failure or resistance breakthrough. The objective of this review is to assess the clinical evidence on the pharmacokinetics and dosage recommendations of the main antibiotic groups used in MRSA treatment in patients treated with CRRT.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones Estafilocócicas
/
Terapia de Reemplazo Renal
/
Staphylococcus aureus Resistente a Meticilina
/
Lesión Renal Aguda
/
Antibacterianos
Tipo de estudio:
Guideline
Límite:
Humans
Idioma:
Es
Revista:
Enferm Infecc Microbiol Clin
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
/
MICROBIOLOGIA
Año:
2012
Tipo del documento:
Article