Modifications in ventricular fibrillation and capture capacity induced by a linear radiofrequency lesion.
Rev Esp Cardiol (Engl Ed)
; 65(2): 143-51, 2012 Feb.
Article
en En, Es
| MEDLINE
| ID: mdl-22177961
ABSTRACT
INTRODUCTION AND OBJECTIVES:
An analysis was made of the effects of a radiofrequency-induced linear lesion during ventricular fibrillation and the capacity to capture myocardium through high-frequency pacing.METHODS:
Using multiple epicardial electrodes, ventricular fibrillation was recorded in 22 isolated perfused rabbit hearts, analyzing the activation maps upon applying trains of stimuli at 3 different frequencies close to that of the arrhythmia a) at baseline; b) after radio-frequency ablation to induce a lesion of the left ventricular free wall (length=10 [1] mm), and c) after lengthening the lesion (length=23 [2] mm).RESULTS:
Following lesion induction, the regularity of the recorded signals decreased and significant variations in the direction of the activation fronts were observed. On lengthening the lesion, there was a slight increase in the episodes with at least 3 consecutive captures when pacing at cycles 10% longer than the arrhythmia (baseline 0.6 [0.7]; initial lesion 1 [1], no significant differences; lengthened lesion 3 [2.8]; P<.001), while a decrease was observed in those obtained upon pacing at cycles 10% shorter than the arrhythmia.CONCLUSIONS:
The radio-frequency -induced lesion increases the heterogeneity of myocardial activation during ventricular fibrillation and modifies arrival of the activation fronts in the adjacent zones. High-frequency pacing during ventricular fibrillation produces occasional captures during at least 3 consecutive stimuli. The lengthened lesion in turn slightly increases capture capacity when using cycles slightly longer than the arrhythmia.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ondas de Radio
/
Fibrilación Ventricular
/
Ablación por Catéter
Límite:
Animals
Idioma:
En
/
Es
Revista:
Rev Esp Cardiol (Engl Ed)
Año:
2012
Tipo del documento:
Article
País de afiliación:
España