Long-term effectiveness and safety of small gel particle hyaluronic acid for hand rejuvenation.
Dermatol Surg
; 38(7 Pt 2): 1128-35, 2012 Jul.
Article
en En
| MEDLINE
| ID: mdl-22243484
ABSTRACT
BACKGROUND:
Fillers to reverse the effects of fat atrophy can help restore the hands' youthful appearance.OBJECTIVE:
To evaluate the effectiveness and safety of small gel particle hyaluronic acid (SGP-HA) for hand rejuvenation through 1 year. MATERIALS ANDMETHODS:
A prospective open-label study recruited adults with moderate to severe vascular, bony, and tendon prominence. After a topical anesthetic was applied, SGP-HA (maximum dose of 4.0 mL) was injected into the dorsum using a threading technique and distributed by massage.RESULTS:
There were 16 patients with a mean ± SD age of 60.1 ± 5.3. Two weeks after treatment, vascular, tendon, and bony prominence and skin turgor were improved by 60.9%, 65.2%, 73.7%, and 26.3%, respectively. Substantial or complete global aesthetic improvement was rated in 75% of patients by investigators and in 56% by self-report; 81% of patients were satisfied or very satisfied. Five needed a touch-up (maximum 1.0 mL/hand). Improvements were largely maintained at 6 months, with 85% patient satisfaction, and assessments approached pretreatment levels at 1 year, with 50% patient satisfaction. One patient reported itching on one hand, which was judged to be unrelated to treatment.CONCLUSION:
SGP-HA produced lasting improvements in aging hands and was safe and well tolerated.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Rejuvenecimiento
/
Atrofia
/
Mano
/
Ácido Hialurónico
Tipo de estudio:
Observational_studies
Límite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Dermatol Surg
Asunto de la revista:
DERMATOLOGIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos