Unusual reaction to chlorambucil: a case report.
Cancer Lett
; 54(3): 109-11, 1990 Nov 05.
Article
en En
| MEDLINE
| ID: mdl-2224838
ABSTRACT
In this brief report we describe a case of cutaneous reaction during treatment of chronic lymphatic leukemia (CLL) with chlorambucil. The patient developed a confluent maculopapular erythema and large flaccid bullae of trunk, legs, feet and mucous membranes, with fever up to 38 degrees C. Toxic epidermal necrolisis (TEN) was supposed and the diagnosis was confirmed by a skin patch test followed by cutaneous biopsy. TEN by chlorambucil is a rare syndrome that may be considered in presence of cutaneous reaction to this drug.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Clorambucilo
/
Síndrome de Stevens-Johnson
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Cancer Lett
Año:
1990
Tipo del documento:
Article
País de afiliación:
Italia