"Sulfolefin": highly modular mixed S/olefin ligands for enantioselective Rh-catalyzed 1,4-addition.
Org Biomol Chem
; 10(12): 2366-8, 2012 Mar 28.
Article
en En
| MEDLINE
| ID: mdl-22277929
ABSTRACT
Reported is a single high yielding step approximation to mixed olefin/sulfinamide ligands enclosing a chiral sulfur atom as the sole chiral center. The synthetic design is validated by a rapid optimization of the substituent at the sulfinyl sulfur, and by the synthesis of an efficient, highly enantioselective catalyst for the Rh-catalyzed 1,4-addition of boronic acids to both, cyclic and acyclic olefins.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Org Biomol Chem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2012
Tipo del documento:
Article
País de afiliación:
España