[Osteoclast-like giant cell tumor (OGCT) of the liver: report of a case].
Nihon Shokakibyo Gakkai Zasshi
; 109(2): 255-62, 2012 Feb.
Article
en Ja
| MEDLINE
| ID: mdl-22306549
ABSTRACT
A 57-year-old man presented with jaundice. Abdominal computed tomography showed a 10-cm left hepatic lobe heterogeneous solid mass with low attenuated areas in the mass, multiple liver metastases and lung metastasis. Serology for hepatitis B and C were negative. Serum alpha-fetoprotein, CEA and CA19-9 were normal. The patient died a few weeks later of progressive liver failure and an autopsy was performed. Histologically, the tumor consisted of sarcomatoid mononuclear cells and osteoclast-like giant cells. The liver tissue surrounding the tumor showed no cirrhotic pattern. The osteoclast-like giant cells were uniformly and strongly immunoreactive with CD68. The mononuclear cells demonstrated expression of vimentin but were negative for CAM5.2. The MIB-1 index was 20% for the mononuclear cells. In conclusion, the histopathological diagnosis revealed an osteoclast-like giant cell tumor of the liver.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tumores de Células Gigantes
/
Neoplasias Hepáticas
Límite:
Humans
/
Male
/
Middle aged
Idioma:
Ja
Revista:
Nihon Shokakibyo Gakkai Zasshi
Año:
2012
Tipo del documento:
Article