Emotional impairment in a patient with amyotrophic lateral sclerosis: a (99m)Tc-HMPAO SPET brain study.
Hell J Nucl Med
; 15(1): 59-62, 2012.
Article
en En
| MEDLINE
| ID: mdl-22413116
ABSTRACT
Behavioral abnormalities have been reported in patients with amyotrophic lateral sclerosis (ALS) but their aetiology is not yet clearly defined. We report on the case of a 48 years old woman with long standing bulbar onset ALS referred to our department for brain perfusion scan for the evaluation of behavioral and emotional disorders. The patient's scores on the neuropsychological tests were satisfactory while magnetic resonance imaging showed no structural brain abnormalities. However, cerebral blood flow imaging with single photon emission tomography with technetium-99m-hexamethyl propylamine oxime demonstrated bilateral frontal cortex hypoperfusion, as well as perfusion defects in the left parietal, temporal and occipital lobes. In conclusion, the reduced regional cerebral blood flow in the frontal lobes might be suggestive of underlying cortical disturbance and potentially explain the patient's symptoms.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Tomografía Computarizada de Emisión de Fotón Único
/
Exametazima de Tecnecio Tc 99m
/
Síntomas Afectivos
/
Esclerosis Amiotrófica Lateral
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Hell J Nucl Med
Asunto de la revista:
MEDICINA NUCLEAR
Año:
2012
Tipo del documento:
Article
País de afiliación:
Grecia