Allylic C-H activations using Cu(II) 2-quinoxalinol salen and tert-butyl hydroperoxide.
J Org Chem
; 77(10): 4628-33, 2012 May 18.
Article
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| MEDLINE
| ID: mdl-22563758
ABSTRACT
Using a Cu(II) 2-quinoxalinol salen complex as the catalyst and tert-butyl hydroperoxide (TBHP) as the oxidant, allylic activations of olefin substrates can be converted to the corresponding enones or 1,4-enediones. Excellent yields can be achieved (up to 99%) within a very short reaction time and with great tolerance for additional functional groups. Possible mechanistic pathways have been characterized using Raman spectroscopy, cyclic voltammetry, and theoretical calculations.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
J Org Chem
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos