Effect of antenatal treatment of maternal periodontitis on early childhood neurodevelopment.
Am J Perinatol
; 29(10): 815-21, 2012 Nov.
Article
en En
| MEDLINE
| ID: mdl-22773286
ABSTRACT
OBJECTIVE:
To determine if antenatal treatment of maternal periodontitis affects early childhood neurodevelopment. STUDYDESIGN:
We evaluated neurodevelopment of 331 24-month-old children born to women who participated in a randomized trial of antenatal (167) or postpartum (164) treatment of periodontitis. Children within groups defined by maternal treatment were designated as high risk for abnormal neurodevelopment (n = 96; birth at ≤34(6)/7 weeks' gestation or small for gestational age following birth at term) or low risk (n = 235; appropriate birth weight and ≥37 weeks' gestation). We measured neurodevelopment using the Bayley Scale of Infant and Toddler Development III (BSID III) and neurological examination. Treatment effect was analyzed using a chi-square or Fisher exact test. Between-group mean scores were compared using Student t test.RESULTS:
There were no differences in the incidence of neuromotor or sensory (visual or hearing) impairment or scores on the BSID III between groups. Low-risk children in the antenatal treatment group had higher language scores than those in the postpartum treatment group (92.9 versus 89.2; p = 0.05).CONCLUSION:
Antenatal treatment of maternal periodontitis does not appear to affect neurodevelopment at 24 months of age. The slight improvement in language development in low-risk children may be an artifact or not clinically relevant.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Periodontitis
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Complicaciones del Embarazo
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Trastornos Psicomotores
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Curetaje Subgingival
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Desarrollo Infantil
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Sistema Nervioso
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
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Etiology_studies
/
Incidence_studies
/
Prognostic_studies
Límite:
Adolescent
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Adult
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Child, preschool
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Female
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Humans
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Infant
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Newborn
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Pregnancy
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Am J Perinatol
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos