Expression of TLR9 and BD-2 protein genes in corneal cells of mice of different strains with herpetic keratitis.
Bull Exp Biol Med
; 153(2): 236-9, 2012 Jun.
Article
en En, Ru
| MEDLINE
| ID: mdl-22816092
ABSTRACT
The dynamics of gene expression of two proteins, TLR9 (one of the key receptors recognizing CpG repeats of herpes virus DNA) and ß-defensin 2 (antibacterial peptide), was studied on the model of herpetic keratitis in C57Bl/6 and BALB/c mice. New data on differences in TLR9 gene expression in mice of the two strains infected with the virus were obtained. Reduced TLR9 gene expression in the cornea of C57Bl/6 mice was associated with their high sensitivity to infection caused by herpes simplex 1 virus.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Expresión Génica
/
Queratitis Herpética
/
Córnea
/
Beta-Defensinas
/
Receptor Toll-Like 9
Límite:
Animals
Idioma:
En
/
Ru
Revista:
Bull Exp Biol Med
Año:
2012
Tipo del documento:
Article
País de afiliación:
Rusia