Use of biomarkers or echocardiography in pulmonary embolism: the Swiss Venous Thromboembolism Registry.
QJM
; 105(12): 1163-9, 2012 Dec.
Article
en En
| MEDLINE
| ID: mdl-22908319
ABSTRACT
BACKGROUND:
Cardiac biomarkers and echocardiography for assessing right ventricular function are recommended to risk stratify patients with acute non-massive pulmonary embolism (PE), but it remains unclear if these tests are performed systematically in daily practice. DESIGN ANDMETHODS:
Overall, 587 patients with acute non-massive PE from 18 hospitals were enrolled in the Swiss Venous Thromboembolism Registry (SWIVTER) 178 (30%) neither had a biomarker test nor an echocardiographic evaluation, 196 (34%) had a biomarker test only, 47 (8%) had an echocardiogram only and 166 (28%) had both tests.RESULTS:
Among the 409 (70%) patients with biomarkers or echocardiography, 210 (51%) had at least one positive test and 67 (16%) had positive biomarkers and right ventricular dysfunction. The ICU admission rates were 5.1% without vs. 5.6% with testing (P = 0.78), and thrombolysis or embolectomy were performed in 2.8% vs. 4.9%, respectively (P = 0.25). In multivariate analysis, syncope [odds ratio (OR) 3.49, 95% confidence interval (CI) 1.20-10.15; P = 0.022], tachycardia (OR 2.31, 95% CI 1.37-3.91; P = 0.002) and increasing age (OR 1.02; 95% CI 1.01-1.04; P < 0.001) were associated with testing of cardiac risk; outpatient status at the time of PE diagnosis (OR 2.24, 95% CI 1.49-3.36; P < 0.001), cancer (OR 1.81, 95% CI 1.17-2.79; P = 0.008) and provoked PE (OR 1.58, 95% CI 1.05-2.40; P = 0.029) were associated with its absence.CONCLUSION:
Although elderly patients and those with clinically severe PE were more likely to receive a biomarker test or an echocardiogram, these tools were used in only two-thirds of the patients with acute non-massive PE and rarely in combination.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Embolia Pulmonar
/
Ecocardiografía
/
Disfunción Ventricular Derecha
/
Medición de Riesgo
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
QJM
Asunto de la revista:
MEDICINA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Suiza