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Frightening music triggers rapid changes in brain monoamine receptors: a pilot PET study.
Zhang, Ying; Chen, Qiaozhen; Du, Fenglei; Hu, Yanni; Chao, Fangfang; Tian, Mei; Zhang, Hong.
Afiliación
  • Zhang Y; Department of Nuclear Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. hzhang21@gmail.com
J Nucl Med ; 53(10): 1573-8, 2012 Oct.
Article en En | MEDLINE | ID: mdl-22933818
UNLABELLED: Frightening music can rapidly arouse emotions in listeners that mimic those from actual life-threatening experiences. However, studies of the underlying mechanism for perceiving danger created by music are limited. METHODS: We investigated monoamine receptor changes induced by frightening music using (11)C-N-methyl-spiperone ((11)C-NMSP) PET. Ten healthy male volunteers were included, and their psychophysiologic changes were evaluated. RESULTS: Compared with the baseline condition, listening to frightening music caused a significant decrease in (11)C-NMSP in the right and left caudate nuclei, right limbic region, and right paralimbic region; a particularly significant decrease in the right anterior cingulate cortex; but an increase in the right frontal occipital and left temporal lobes of the cerebral cortex. CONCLUSION: Transient fright triggers rapid changes in monoamine receptors, which decrease in the limbic and paralimbic regions but increase in the cerebral cortex.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Receptores de Amina Biogénica / Tomografía de Emisión de Positrones / Miedo / Música Tipo de estudio: Clinical_trials Límite: Adult / Humans / Male Idioma: En Revista: J Nucl Med Año: 2012 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Receptores de Amina Biogénica / Tomografía de Emisión de Positrones / Miedo / Música Tipo de estudio: Clinical_trials Límite: Adult / Humans / Male Idioma: En Revista: J Nucl Med Año: 2012 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos