Encapsulation and release of hydrophobic bioactive components in nanoemulsion-based delivery systems: impact of physical form on quercetin bioaccessibility.
Food Funct
; 4(1): 162-74, 2013 Jan.
Article
en En
| MEDLINE
| ID: mdl-23172078
ABSTRACT
Many bioactive compounds are hydrophobic materials that are crystalline at ambient and body temperatures, which reduces their bioavailability and poses challenges to their successful incorporation into pharmaceuticals and functional foods. The aim of this study was to determine whether a hydrophobic crystalline bioactive component (quercetin) could be successfully incorporated into nanoemulsion-based delivery systems, and to evaluate the extent to which these delivery systems altered its bioaccessibility. The maximum amount of soluble quercetin that could be loaded into a carrier oil phase (medium chain triglycerides, MCT) at ambient temperature was C(Sat)≈ 0.15 mg mL(-1). At quercetin concentrations
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quercetina
/
Nanopartículas
Idioma:
En
Revista:
Food Funct
Año:
2013
Tipo del documento:
Article