Changes of myelinated nerve and myelin basic protein expression in rats' periodontal ligaments after experimental tooth movement.
Am J Orthod Dentofacial Orthop
; 142(6): 814-24, 2012 Dec.
Article
en En
| MEDLINE
| ID: mdl-23195367
ABSTRACT
INTRODUCTION:
Information about the effect of tooth movement on the myelinated nerve in the periodontal ligament is limited. In this study, we aimed to investigate what responses of the periodontal myelinated nerve can be evoked during experimental tooth movement.METHODS:
In experimental-I group, the maxillary left and mandibular right third molars were moved distally. In experimental-II group, the maxillary left third molar but not the right one was moved, and the bilateral mandibular third molars were extracted. The ultrastructures of the myelinated nerve in the periodontal ligament of the bilateral maxillary third molars were observed under a transmission electron microscope. The expression of myelin basic protein was evaluated by immunohistochemistry.RESULTS:
Degenerative ultrastructural changes of the myelinated nerve in the periodontal ligament were noticed mainly in the myelin sheath; these were observed earlier and were recoverable in the experimental-I group. In contrast, the ultrastructural changes of the myelinated nerve occurred mainly in the axons, were observed later, and were unrecoverable in the experimental-II group. A concomitant decrease of myelin basic protein expression was observed in both groups.CONCLUSIONS:
Both experimental tooth movement and occlusal changes accompanying it caused changes of the myelinated nerve in the periodontal ligament.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ligamento Periodontal
/
Técnicas de Movimiento Dental
/
Proteína Básica de Mielina
/
Fibras Nerviosas Mielínicas
Límite:
Animals
Idioma:
En
Revista:
Am J Orthod Dentofacial Orthop
Asunto de la revista:
ODONTOLOGIA
/
ORTODONTIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
China