Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention.
Public Health Nutr
; 17(2): 440-9, 2014 Feb.
Article
en En
| MEDLINE
| ID: mdl-23249766
ABSTRACT
OBJECTIVE:
The current study aimed to evaluate the effect of fortified milk combined with a lifestyle and counselling programme on several CVD risk factors after a 3-month dietary intervention.DESIGN:
Hypercholesterolaemic adults were randomized to a group supplemented with low-fat milk that was enriched with phytosterols, α-linolenic and linoleic fatty acids, vitamins and antioxidants (enriched milk group, EMG n 40), a placebo milk group (PMG n 36) or a control group (CG n 25). The EMG and PMG consumed respectively 500 ml of enriched milk or placebo milk daily and attended biweekly counselling sessions over a 3-month period.SETTING:
Harokopio University, Athens, Greece.SUBJECTS:
A sample of 101 hypercholesterolemic adults aged 40-60 years.RESULTS:
Regarding lifestyle changes, total and saturated fat intakes decreased significantly in both intervention groups compared with the CG (P < 0·005). Furthermore, total steps were increased (P = 0·029) and BMI was decreased (P = 0·017) significantly in both intervention groups compared with the CG. Regarding biochemical indices, EPA content in erythrocyte membranes increased (P < 0·001) while serum C-reactive protein decreased (P = 0·003) significantly in both intervention groups compared with the CG. Finally, significant increases in plasma folic acid and vitamin B12 levels and a significant decrease in homocysteine levels were observed in the EMG compared with the PMG and CG (all P < 0·001). A favourable change in LDL cholesterolHDL cholesterol was also observed in the EMG and tended to be significant compared with the PMG and CG (P = 0·066).CONCLUSIONS:
The present study showed that consumption of fortified milk accompanied with lifestyle counselling induces extra benefits in terms of LDL cholesterolHDL cholesterol and serum homocysteine levels.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
/
Alimentos Fortificados
/
Leche
/
Estilo de Vida
Tipo de estudio:
Clinical_trials
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Etiology_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Animals
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Public Health Nutr
Asunto de la revista:
CIENCIAS DA NUTRICAO
/
SAUDE PUBLICA
Año:
2014
Tipo del documento:
Article
País de afiliación:
Grecia