Pharmacokinetics of aspirin in aged Indians.
Eur J Clin Pharmacol
; 38(1): 85-6, 1990.
Article
en En
| MEDLINE
| ID: mdl-2328753
The pharmacokinetics of aspirin (ASA) has been studied in elderly Indians (greater than 60 y) of either sex, composing, apparently healthy subjects controlled hypertensives and NIDDM diabetics, in comparison with healthy young subjects. Serum salicylate levels were estimated a 0, 0.5, 1, 2, 4 & 8 h after ASA. The pharmacokinetics of serum salicylate were not changed in elderly subjects as compared to the young after the first dose or after one week of ASA therapy, although greater variability was observed in the elderly. Various laboratory investigations were unaltered after one week in all the groups, except that one elderly hypertensive patient gained weight, and a young subject showed an increase in SGOT & SGPT.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aspirina
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
Eur J Clin Pharmacol
Año:
1990
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
Alemania