Effect of gadobutrol on VX2 magnetic resonance diffusion-weighted imaging.
Annu Int Conf IEEE Eng Med Biol Soc
; 2012: 384-7, 2012.
Article
en En
| MEDLINE
| ID: mdl-23365910
ABSTRACT
The aim of this study was to evaluate the effect of contrast agent gadobutrol on the magnetic resonance diffusion-weighted imaging (MR DWI). Gadobutrol has higher relaxivity than Gd-DTPA and it also has higher formulation 1.0 M than Gd-DTPA 0.5 M. VX2 tumor implanted on the left thigh of each New Zealand rabbit was used as the animal model. The MR scanning was performed using a 1.5 T clinical whole-body MR scanner with an 8-channel knee coil. The results showed that there were significant differences in the signal-to-noise ratio (SNR) and apparent diffusion coefficient (ADC) values between tumor and muscle both before and after gadobutrol injection (0.1 mmol/kg). However, there were no significant differences in the SNR and ADC values of tumor or muscle before and after gadobutol administration. There were also no significant difference in the contrast-to-noise ratio (CNR) values of tumor and muscle before and after gadobutrol injection.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos Organometálicos
/
Medios de Contraste
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Imagen de Difusión por Resonancia Magnética
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Relación Señal-Ruido
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Neoplasias
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
Annu Int Conf IEEE Eng Med Biol Soc
Año:
2012
Tipo del documento:
Article