Association of Morbus Ledderhose with Dupuytren's contracture.
Foot Ankle Int
; 34(6): 841-5, 2013 Jun.
Article
en En
| MEDLINE
| ID: mdl-23386754
ABSTRACT
BACKGROUND:
Fibromatous nodules in the sole of the foot are often called Ledderhose disease. It is a benign nodular formation in the plantar aponeurosis, typically at the distal medial border. A lump forms and it can be a few centimeters in diameter. It is frequently seen as an isolated disease, but a relationship to Dupuytren's has been noted in some patients.METHODS:
The study was a part of a large cohort study, the Reykjavík study. Men with Dupuytren's disease (n = 122) were invited to follow-up 18 years after the initial observation. An equal number of controls, matched for age and smoking habits, were also invited. A total of 92 Dupuytren's patients and 101 control subjects attended for follow-up and were examined for plantar nodules. Statistical evaluation was carried out using chi-square test and presented as odds ratio (OR) and 95% confidence interval (95% CI).RESULTS:
Ledderhose disease was identified in 14 of the 92 (15.2%) men with Dupuytren's disease, while it was only in 4 of the 101 (3.9%) matched controls (OR = 4.35, 95% CI, 1.3-16.7, P < 0.01). Men operated for Dupuytren's disease or with finger contractures were more likely to have plantar nodules than those with only nodules or strings in the palms (OR = 6.1, 95% CI, 1.8-27.1, P < 0.001). The plantar involvement was related to family history of Dupuytren's disease (OR = 3.1, 95% CI, 1.1-8.5, P = 0.02).CONCLUSION:
Men with manifestations of finger contractures or who need surgery for Dupuytren's disease are more likely to also develop plantar fibromas. LEVEL OF EVIDENCE Level III, retrospective comparative series.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Contractura de Dupuytren
/
Fibroma
/
Enfermedades del Pie
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Foot Ankle Int
Asunto de la revista:
ORTOPEDIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Islandia