Renal denervation for refractory hypertension - technical aspects, complications and radiation exposure.
Rofo
; 185(6): 550-7, 2013 Jun.
Article
en En
| MEDLINE
| ID: mdl-23471681
ABSTRACT
PURPOSE:
To analyze procedural details, complications and radiation exposure in renal denervation (RDN) using the Medtronic Symplicity® device in the treatment of refractory hypertension. MATERIALS ANDMETHODS:
Fifty three consecutive patients underwent RDN. The number of ablations per artery, peri-procedural complications, procedure time (PT), fluoroscopy time (FT), dose-area product (DAP) and procedure-related complications were documented. Additionally, the radiation dose was compared between obese (body mass index ≥ 30 kg/m(2)) and non-obese patients.RESULTS:
Bilateral RDN was performed in 50/53 (94 %) cases and with a minimum of 4 ablations per artery in 33/50 (66 %), the mean count being 5.4 (range R 2 - 13) on the right and 4.3 (R 1 - 10) on the left. The FT and DAP decreased significantly over the first 12 procedures, reaching a steady state with a median FT of 11.2 min (R 7.5 - 27) and a median DAP of 4796 cGy × cm(2) (R 1076 - 21 371), resulting in an effective dose of 15.7 mSv. The median PT was 57 min (R 40 - 70). Obese patients had a 3.3-fold higher radiation dose (p < 0.001). We observed one severe spasm and one imminent respiratory depression, both resolved without sequelae.CONCLUSION:
For an experienced interventionalist, RDN has a short learning curve with a low risk profile. The radiation dose does not exceed that of other renal artery interventions, but is explicitly higher in obese patients, who account for a large portion of patients with refractory hypertension.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ablación por Catéter
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Desnervación
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Hipertensión
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Riñón
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Rofo
Año:
2013
Tipo del documento:
Article