Nanopatterned polymer brushes as switchable bioactive interfaces.
Nanoscale
; 5(9): 3632-7, 2013 May 07.
Article
en En
| MEDLINE
| ID: mdl-23532384
ABSTRACT
We report convenient methods for synthesis of nanopatterned, thermally responsive brushes of poly(N-isopropyl acrylamide) over large areas (e.g., 1 cm(2)) to form model, dynamic, biofunctional surfaces. The new nanopatterned brush structure can be used to control (i) the rate of both nonspecific and biospecific adsorption processes at the polymer-graft-free regions of the substrate, and (ii) the rate of cell detachment. These capabilities have potential implications in a number of areas of biotechnology including biosensing, separations and cell culture.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polímeros
/
Acrilamidas
Límite:
Animals
Idioma:
En
Revista:
Nanoscale
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos