Antibiotics for brain abscesses in people with cyanotic congenital heart disease.
Cochrane Database Syst Rev
; (3): CD004469, 2013 Mar 28.
Article
en En
| MEDLINE
| ID: mdl-23543532
ABSTRACT
BACKGROUND:
Brain abscess is a focal, intracerebral infection that begins as a localized area of brain infection and develops into a collection of pus surrounded by a well-vascularized capsule. People with cyanotic congenital heart disease are at risk of developing brain abscess.OBJECTIVES:
To evaluate the effectiveness of antibiotic regimens for treating brain abscess in people with cyanotic congenital heart disease. SEARCHMETHODS:
We updated the searches of the Cochrane Central Register of Controlled Trials (CENTRAL) on The Cochrane Library Issue 12 of 12, December 2012, MEDLINE Ovid (1946 to December Week 4 2012), EMBASE Ovid (1980 to 2013 Week 01) and LILACS (1980 to 9 January 2013) on 9 January 2013. No language or publication restrictions were applied. SELECTION CRITERIA Randomized controlled trials that reported clinically meaningful outcomes and presented results on an intention to treat basis, irrespective of blinding, publication status, or language. DATA COLLECTION ANDANALYSIS:
Data were to be extracted, unblinded, by the two reviewers independently. MAINRESULTS:
No studies meeting the inclusion criteria were identified. AUTHORS'CONCLUSIONS:
There are no randomized controlled trials about the effectiveness of antibiotic regimens for treating people with cyanotic congenital heart disease who developed a brain abscess. Currently, the antibiotic regimens used are based on previous retrospective studies and clinical experience. There is a need for a well designed multicentre randomized controlled trial to evaluate the effects of different antibiotic regimens.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Absceso Encefálico
/
Cardiopatías Congénitas
/
Antibacterianos
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Cochrane Database Syst Rev
Asunto de la revista:
PESQUISA EM SERVICOS DE SAUDE
Año:
2013
Tipo del documento:
Article
País de afiliación:
Tailandia