[Effects of long-term intervention of moxa smoke on T lymphocyte subsets and CD4+ CD25+ Treg in peripheral blood of Wistar rats].
Zhongguo Zhen Jiu
; 33(2): 145-8, 2013 Feb.
Article
en Zh
| MEDLINE
| ID: mdl-23620944
ABSTRACT
OBJECTIVE:
To investigate the cellular immune regulation of the long-term intervention of moxa smoke.METHODS:
Thirty-two Wistar rats were randomly divided into a blank group, a low concentration group, a medium concentration group and a high concentration group, 8 cases in each group. In addition to the blank group, rats in the other groups were exposed to the corresponding concentration moxa smoke for 20 min every day, the T lymphocyte subsets and proportion of the CD4+ CD25+ Treg in CD4+ T cells in peripheral blood were tested by flow cytometry after 6 months.RESULTS:
Compared with the blank group, the proportions of CD3+ CD4+, CD3+ CD8+ T cells and CD3+ CD4/CD3+ CD8+ in the other 3 moxa smoke groups were not significantly different (P > 0.05), while the proportions of the CD4+ CD25+ Treg in CD4+ T cells were significantly lower (P < 0.05), but no statistically significant differences among those 3 moxa smoke intervention groups (P > 0.05).CONCLUSION:
Long-term moxa smoke intervention has no significant effect on the proportions of CD3+ CD4+, CD3+ CD8+ T cells and CD3+ CD4+/CD3+ CD8+, but it can decrease the proportions of the CD4+ CD25+ Treg in CD4+ T cells in peripheral blood of rats. The way produced by pretreatment with moxa smoke may play immunomodulatory effect.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Humo
/
Subgrupos de Linfocitos T
/
Linfocitos T Reguladores
/
Moxibustión
Límite:
Animals
Idioma:
Zh
Revista:
Zhongguo Zhen Jiu
Asunto de la revista:
TERAPIAS COMPLEMENTARES
Año:
2013
Tipo del documento:
Article
País de afiliación:
China