Cerebral infarction in an HIV-infected patient with combined protein S and C deficiency and a patent foramen ovale.
J Stroke Cerebrovasc Dis
; 22(8): e650-2, 2013 Nov.
Article
en En
| MEDLINE
| ID: mdl-23664714
ABSTRACT
A 41-year-old male with a history of human immunodeficiency virus (HIV) infection developed motor aphasia, dysarthria, and right hemiparesis. A magnetic resonance imaging scan of the brain revealed a cerebral infarction in the territory of the left middle cerebral artery. The laboratory data showed decreased levels of protein S and protein C. Transesophageal contrast-enhanced echocardiography revealed a patent foramen ovale (PFO). Prothrombotic states, such as protein S and C deficiency, have been reported in HIV-infected patients. In addition, previous studies have reported prothrombotic states to be risk factors for PFO-related cerebral infarction. An association between combined protein S and C deficiency caused by HIV infection and PFO-related cerebral infarction was suggested in our patient.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones por VIH
/
Deficiencia de Proteína S
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Deficiencia de Proteína C
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Infarto de la Arteria Cerebral Media
/
Foramen Oval Permeable
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
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Humans
/
Male
Idioma:
En
Revista:
J Stroke Cerebrovasc Dis
Asunto de la revista:
ANGIOLOGIA
/
CEREBRO
Año:
2013
Tipo del documento:
Article
País de afiliación:
Japón